Chronic infection may indirectly influence the risk of atherosclerosis and thrombosis Figure by the following 1 increased systemic inflammation, which in turn may damage vascular walls eg, by cytokines and proteases and lead to a procoagulant state 146; 2 immune mediated mechanisms, eg, molecular mimicry, possibly including a cross reaction of antibodies between human and bacterial structures such as heat shock proteins 84, 147; 3 recurrent bacteremia eg, periodontitis, which may induce platelet activation and a procoagulant state 148; and 4 influence on risk factors, eg, alteration of serum lipids toward a more proatherogenic profile buy priligy pills Using a model available through the American Society of Breast Surgeons, and entering the following information provided by you, your surgeon can calculate how likely it is that you will develop breast cancer in the next 5 years, as well as in your lifetime